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sgugenetics / -Sickle Cell Disease-
sgugenetics / -Sickle Cell Disease-

Single nucleotide polymorphisms (SNPs) in causing β-thalassemia
Single nucleotide polymorphisms (SNPs) in causing β-thalassemia

Supramolecular nanosubstrate–mediated delivery system enables CRISPR-Cas9  knockin of hemoglobin beta gene for hemoglobinopathies | Science Advances
Supramolecular nanosubstrate–mediated delivery system enables CRISPR-Cas9 knockin of hemoglobin beta gene for hemoglobinopathies | Science Advances

File:HBB location.png - Wikipedia
File:HBB location.png - Wikipedia

Beta Thalassemia Causes | Understand Genetics & Inheritance
Beta Thalassemia Causes | Understand Genetics & Inheritance

Identification of seven novel variants in the β-globin gene in  transfusion-dependent and normal patients
Identification of seven novel variants in the β-globin gene in transfusion-dependent and normal patients

What Causes Sickle Cell Disease?
What Causes Sickle Cell Disease?

What Causes Sickle Cell Disease?
What Causes Sickle Cell Disease?

Hemoglobin Disorders
Hemoglobin Disorders

Beta-thalassemia | Genetics in Medicine
Beta-thalassemia | Genetics in Medicine

Figure 1 from HBB FSC 36-37 (-T) Gene Mutation Detection in Carriers of  Thalassemia Minor Using High Resolution Melting Analysis | Semantic Scholar
Figure 1 from HBB FSC 36-37 (-T) Gene Mutation Detection in Carriers of Thalassemia Minor Using High Resolution Melting Analysis | Semantic Scholar

Map of human β-globin (HBB) gene and common indicated mutations along... |  Download Scientific Diagram
Map of human β-globin (HBB) gene and common indicated mutations along... | Download Scientific Diagram

Expression of β-globin by cancer cells promotes cell survival during  blood-borne dissemination | Nature Communications
Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination | Nature Communications

HBB-like gene cluster on chromosome 11 in sickle cell aremia. (A)... |  Download Scientific Diagram
HBB-like gene cluster on chromosome 11 in sickle cell aremia. (A)... | Download Scientific Diagram

Figure 1 from Compound heterozygous β+ β0 mutation of HBB gene leading to  β-thalassemia major in a Gujarati family — A case study | Semantic Scholar
Figure 1 from Compound heterozygous β+ β0 mutation of HBB gene leading to β-thalassemia major in a Gujarati family — A case study | Semantic Scholar

In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using  Alternative Donor Template Delivery Methods: Molecular Therapy - Nucleic  Acids
In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods: Molecular Therapy - Nucleic Acids

Genetic Cause - Sickle Cell Disease
Genetic Cause - Sickle Cell Disease

A Universal Approach to Correct Various HBB Gene Mutations in Human Stem  Cells for Gene Therapy of Beta‐Thalassemia and Sickle Cell Disease - Cai -  2018 - STEM CELLS Translational Medicine - Wiley Online Library
A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta‐Thalassemia and Sickle Cell Disease - Cai - 2018 - STEM CELLS Translational Medicine - Wiley Online Library

David R. Liu on X: "Each year more than 300,000 are born with SCD—the  result of inheriting 2 mutated copies of the HBB gene. The mutated  hemoglobin polymerizes, causing sickle-shaped red blood
David R. Liu on X: "Each year more than 300,000 are born with SCD—the result of inheriting 2 mutated copies of the HBB gene. The mutated hemoglobin polymerizes, causing sickle-shaped red blood

Frontiers | Regulatory Variation in Functionally Polymorphic Globin Genes  of the Bank Vole: A Possible Role for Adaptation
Frontiers | Regulatory Variation in Functionally Polymorphic Globin Genes of the Bank Vole: A Possible Role for Adaptation

Development of Gene Editing Strategies for Human β-Globin (HBB) Gene  Mutations | bioRxiv
Development of Gene Editing Strategies for Human β-Globin (HBB) Gene Mutations | bioRxiv

Sickle Cell Anemia: Genetics and Carrier Information - 23andMe
Sickle Cell Anemia: Genetics and Carrier Information - 23andMe

HBB Gene - GeneCards | HBB Protein | HBB Antibody
HBB Gene - GeneCards | HBB Protein | HBB Antibody